A Randomized Phase II Study of Temozolomide or Temozolomide and Capecitabine in Patients with Advanced Pancreatic Neuroendocrine Tumors
This is a Phase II study that will compare the effects, good and/or bad, of temozolomide versus temozolomide plus capecitabine on advanced pancreatic neuroendocrine tumors cancer to find out which is more effective. In this study, participants will get either temozolomide alone or temozolomide andcapecitabine. Temozolomide and capecitabine are chemotherapy drugs, which have benefited some patients with pancreatic neuroendocrine tumors yet they have never been compared; both arms are considered investigational.