Basic Science Surgery Presentations and Research

This quarterly report is a summary of the monthly Faculty Research Newsletter. Journal links within the publications below may require subscriptions or a log-in through the Columbia library while PubMed links are accessible to all.

Presentations

December 2018

American Heart Association Scientific Sessions
Chicago, November 10, 2018

  • Bayne J, Rubin GA, Takayama H, Takeda K, Naka Y, Farr M, Givens R, Wan EY. Increased Kidney Injury in Black Patients After Cardiac Transplant.
  • Frasca A, Keeney S, Lee S, Bavaria JE, Gorman RC, Levy RJ, Ferrari G. Advanced Glycation End Products and the Pathophysiology of Bioprosthetic Heart Valve Structural Degeneration.
  • Gaudig A, Zuver A, Pinsino A, Naka Y, Takeda K, Garan AR, Topkara VK, Yuzefpolskaya M, Colombo PC, Wiley JZ. Pulse Pressure and Mean Arterial Pressure Are Not Associated With Hemorrhagic Adverse Events in Left Ventricular Assist Device Patients.
  • Grady KL, Okwuosa I, Petty M, Adam H, Pollan L, Andrei AC, Kao A, Pham DT, Yancy C, Dew MA, Kormos R, Hsich E, Cotts W, LaRue S, Pamboukian SV, Pagani FD, Lampert B, Johnson M, Murray M, Takeda K, Yuzefpolskaya M, Spertus J, Kirklin JK, Collum SC, Anderson AS. Sustaining Quality of Life of the Aged: Transplant or Mechanical Support: Baseline Caregiver Quality of Life.
  • Imamura T, Ono M, Fukushima N, Kinugawa K, Shiose A, Marsui Y, Yamazaki K Saiki Y, Usui A, Niinami H, Matsumiya G, Arai H, Sawa Y, Kim G, Sayer G, Naka Y, Jeevandam V, Uriel. Comparison in Hemocompatibility-Related Adverse Events in Patients Supported With Left Ventricular Assist Device Between Japan and United States
  • Kennel PJ, Liao X, Ji R, Zhang X, Castillero E, Brunjes D, Takayama H, Naka Y, Thomas T, George I, Mancini D, Schulze C. Suppression of the Amino Acid Carrier SLC1A5 in Failing Myocardium Results in Decreased Glutamine Levels and Induction of Autophagy.
  • LaPar D, Haddad EA, Chai PJ, Kalfa D, Levasseur S, Lewis M, Rosenbaum M, Singh H, Ginns JN, Bacha E. A Single Center 25-Year Experience With the Ross Procedure in Over 200 Patients.
  • Nakanishi K, Homma S, Han J, Takayama H, Colombo P, Yuzefpolskaya M, Garan A, Farr M, Kurlansky P, Di Tullio M, Naka Y, Takeda K. Prevalence, Predictors and Prognostic Value of Residual Tricuspid Regurgitation in Patients With Left Ventricular Assist Device.
  • Nemeth S, Schnell S, Argenziano M, Kurlansky P. Time of Day Does Not Impact Outcome of Cardiac Surgery: Results from a diverse, multi-institutional cardiac surgery network.
  • Pinsino A, Royzman E, Mabasa M, Zuver AM, Gaudig AJ, Masoumi A, Rosenblum H, Leb J, Garan AR, Topkara VK, Takeda K, Takayama H, Naka Y, Radhakrishnan J, Giles JT. Serum Cystatin C is an Alternative Measure of Renal Function and is Superior to Serum Creatinine for Prediction of Adverse Events in Left Ventricular Assist Device Patients.
  • Siddiqui S, Anderson BR, LaPar DJ, Kalfa D, Chai P, Bacha E, Freud L. Effects of Body Mass Index, Race, and Payer on 1-Year Outcomes Following Congenital Heart Surgery.
  • Yuzefpolskaya M, Nasiri M, Pinsino A, Onat HD, Zuver AM, Nwokocha JK, Royzman EA, Mabasa M, Clemons AM, Castagna F, Garan AR, Brunjes DL, Takeda K, Takayama H, Naka Y, Uhlemann AC, Colombo PC. Preoperative Biomarkers of Inflammation and Oxidative Stress Predict Early Outcomes and Only Modestly Decline After Left Ventricular Assist Device Implantation: A Prospective Study.

Publications

May 2019

  • Israelyan N, Del Colle A, Li Z, Park Y, Xing A, Jacobsen JPR, Luna RA, Jensen DD, Madra M, Saurman V, Rahim R, Latorre R, Law K, Carson W, Bunnett NW, Caron MG, Margolis KG. Effects of Serotonin and Slow-release 5-HTP on Gastrointestinal Motility in a Mouse Model of Depression. Gastroenterology. 2019 Apr 25. pii: S0016-5085(19)36715-0. doi: 10.1053/j.gastro.2019.04.022.
    Journal link | PubMed link
  • Roitman M, Edgington-Mitchell LE, Mangum J, Ziogas J, Adamides AA, Myles P, Choo-Bunnett H, Bunnett NW, Gunnersen JM. Sez6 levels are elevated in cerebrospinal fluid of patients with inflammatory pain-associated conditions. Pain Rep. 2019 Mar 25;4(2):e719. doi: 10.1097/PR9.0000000000000719. eCollection 2019 Mar-Apr.
    Journal link | PubMed link

June 2019

  • Fortier JH, Pizzarotti B, Shaw RE, Levy RJ, Ferrari G, Grau J. Drug-associated valvular heart diseases and serotonin-related pathways: a meta-analysis. Heart. 2019 May 25. pii: heartjnl-2018-314403. doi: 10.1136/heartjnl-2018-314403.
    Journal link | PubMed link

April 2019

  • Canals M, Poole DP, Veldhuis NA, Schmidt BL, Bunnett NW. G Protein-Coupled Receptors are Dynamic Regulators of Digestion and Targets for Digestive Diseases. Gastroenterology. 2019 Feb 13. pii: S0016-5085(19)30373-7. doi: 10.1053/j.gastro.2019.01.266.
    Journal link | PubMed link

December 2018

  • Langer N, Ando M, Simpson M, van Boxtel BS, Sorabella RA, Patel V, George I, Smith CR, Takayama H. Influence of left ventricular ejection fraction on morbidity and mortality after aortic root replacement. J Cardiovasc Thorac Surg, DOI: https://doi.org/10.1016/j.jtcvs.2018.10.147
    Journal link
  • Mulaikal TA, Pospishil L, George I, Bapat VN, Hahn RT. Surgically Assisted Transcatheter Balloon-Expandable Valve in Inferior Vena Cava for Torrential Tricuspid Regurgitation. CASE (Phila). 2018 Jul 13;2(5):174-180. doi: 10.1016/j.case.2018.04.009. eCollection 2018 Oct.
    Journal link | PubMed link
  • Spina R, Khalique O, Kodali S, Bapat VN. Urgent transcatheter aortic valve replacement for severe acute aortic regurgitation following open mitral valve surgery. Catheter Cardiovasc Interv. 2018 Nov 8. doi: 10.1002/ccd.27954.
    Journal link | PubMed link
  • Truby LK, Garan AR, Givens RC, Wayda B, Takeda K, Yuzefpolskaya M, Colombo PC, Naka Y, Takayama H, Topkara VK. Aortic Insufficiency During Contemporary Left Ventricular Assist Device Support: Analysis of the INTERMACS Registry. JACC Heart Fail. 2018 Nov;6(11):951-960. doi: 10.1016/j.jchf.2018.07.012.
    Journal link | PubMed link
  • Yoon SH, Whisenant BK, Bleiziffer S, Delgado V, Dhoble A, Schofer N, Eschenbach L, Bansal E, Murdoch DJ, Ancona M, Schmidt T, Yzeiraj E, Vincent F, Niikura H, Kim WK, Asami M, Unbehaun A, Hirji S, Fujita B, Silaschi M, Tang GHL, Kuwata S, Wong SC, Frangieh AH, Barker CM, Davies JE, Lauten A, Deuschl F, Nombela-Franco L, Rampat R, Nicz PFG, Masson JB, Wijeysundera HC, Sievert H, Blackman DJ, Gutierrez-Ibanes E, Sugiyama D, Chakravarty T, Hildick-Smith D, de Brito FS Jr, Jensen C, Jung C, Smalling RW, Arnold M, Redwood S, Kasel AM, Maisano F, Treede H, Ensminger SM, Kar S, Kaneko T, Pilgrim T, Sorajja P, Van Belle E, Prendergast BD, Bapat V, Modine T, Schofer J, Frerker C, Kempfert J, Attizzani GF, Latib A, Schaefer U, Webb JG, Bax JJ, Makkar RR. Outcomes of transcatheter mitral valve replacement for degenerated bioprostheses, failed annuloplasty rings, and mitral annular calcification. Eur Heart J. 2018 Oct 23. doi: 10.1093/eurheartj/ehy590.
    Journal link | PubMed link

November 2018

  • Thomsen ARB, Jensen DD, Hicks GA, Bunnett NW. Therapeutic Targeting of Endosomal G-Protein-Coupled Receptors. Trends Pharmacol Sci. 2018 Oct;39(10):879-891.
    Journal link | PubMed link

August 2018

  • DiCello JJ, Saito A, Rajasekhar P, Eriksson EM, McQuade RM, Nowell CJ, Sebastian BW, Fichna J, Veldhuis NA, Canals M, Bunnett NW, Carbone SE, Poole DP. Inflammation-associated changes in DOR expression and function in the mouse colon. Am J Physiol Gastrointest Liver Physiol. 2018 Jun 21. doi: 10.1152/ajpgi.00025.2018.
    Journal link | PubMed link
  • Guerrero-Alba R, Valdez-Morales EE, Jiménez-Vargas NN, Bron R, Poole D, Reed D, Castro J, Campaniello M, Hughes PA, Brierley SM, Bunnett N, Lomax AE, Vanner S. Co-expression of μ and δ opioid receptors by mouse colonic nociceptors. Br J Pharmacol. 2018 Jul;175(13):2622-2634. doi: 10.1111/bph.14222.
    Journal link | PubMed link
  • Jimenez-Vargas NN, Pattison LA, Zhao P, Lieu T, Latorre R, Jensen DD, Castro J, Aurelio L, Le GT, Flynn B, Herenbrink CK, Yeatman HR, Edgington-Mitchell L, Porter CJH, Halls ML, Canals M, Veldhuis NA, Poole DP, McLean P, Hicks GA, Scheff N, Chen E, Bhattacharya A, DiCello JJ, Saito A, Rajasekhar P, Eriksson EM, McQuade RM, Nowell CJ, Sebastian BW, Fichna J, Veldhuis NA, Canals M, Bunnett NW, Carbone SE, Poole DP. Inflammation-associated changes in DOR expression and function in the mouse colon. Am J Physiol Gastrointest Liver Physiol. 2018 Jun 21. doi: 10.1152/ajpgi.00025.2018.
    Journal link | PubMed link
  • Marone IM, De Logu F, Nassini R, De Carvalho Goncalves M, Benemei S, Ferreira J, Jain P, Li Puma S, Bunnett NW, Geppetti P, Materazzi S. TRPA1/NOX in the soma of trigeminal ganglion neurons mediates migraine-related pain of glyceryl trinitrate in mice. Brain. 2018 Jul 6. doi: 10.1093/brain/awy177.
    Journal link | PubMed link

January 2018

  • De Logu F, Nassini R, Materazzi S, Carvalho Gonçalves M, Nosi D, Rossi Degl'Innocenti D, Marone IM, Ferreira J, Li Puma S, Benemei S, Trevisan G, Souza Monteiro de Araújo D, Patacchini R, Bunnett NW, Geppetti P. Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice. Nat Commun. 2017 Dec 1;8(1):1887. doi: 10.1038/s41467-017-01739-2.
    Journal link | PubMed link